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Compositions having anti-leishmanial activity
   
Document Number
US Patent 6433023
Issued Date
August 13, 2002
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Abstract
This invention is directed to a composition comprising 4-chloro-3,6-dinitrobenzotrifluoride and related compounds and method for using it to treat infections caused by organisms that have microtubules.
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Number of Claims:
15
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Published
August 13, 2002
Application Number
09/048,334
Filed
March 26, 1998
US Classification
514/706   514/741
Int'l Classification
A61K   31/095   (20060101)  
Examiner
Attorney/Law Firm
Parent Case
This application takes priority from Provisional Application No. 60/042,267, filed Mar. 31, 1997.
USPTO Field of Search
514/706   514/741  
Related Patents
7186702 - Method of treating leishmaniasis using methyl-beta-cyclodextrin - Owned by Council of Scientific and Industrial Research (New Delhi,IN)

The present invention relates to a composition useful for the treatment of leishmaniasis said composition comprising pharmaceutically effective amount of methyl-beta-cyclodextrin, optionally along with other anti-leishmanial agent(s) and/or pharmaceutically acceptable additives, and a method thereof, wherein the said method reduces the cholesterol levels of the plasma membrane of the infected host cells by about 50%.

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Description
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