September 10, 2002

The invention relates to the use of cannabinoid compounds (derivatives of tetrahydrocannabinol) for decreasing cell proliferation in a mammal.

16

September 10, 2002

09/851,122

May 8, 2001

514/454  

A61K   31/185   (20060101)   A61K   31/20   (20060101)   A61K   31/19   (20060101)   A61K   31/35   (20060101)  

CROSS-REFERENCE TO RELATED APPLICATIONS This application claims priority from U.S. Provisional Application Ser. No. 60/204,935, filed May 17, 2000.

514/454  

7169942 - Cannabinoid derivatives, methods of making, and use thereof - Owned by University of Tennessee Research Foundation (Knoxville, TN) 1'-substituted cannabinoid derivatives of delta-8-tetrahydrocannabinol, delta-9-tetrahydrocannabinol, and delta-6a-10a-tetrahydrocannabinol that have affinity for the cannabinoid receptor type-1 (CB-1) and/or cannabinoid receptor type-2 (CB-2). Compounds having activity as either agonists or antagonists of the CB-1 and/or CB-2 receptors can be used for treating CB-1 or CB-2 mediated conditions.