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Method and composition of an oral preparation of itraconazole
   
Document Number
US Patent 6485743
Issued Date
November 26, 2002
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Inventors
Kim; Kye-Hyun (Kyunggi-do,KR)
Lee; Kyu-Hyun (Kyunggi-do,KR)
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Abstract
The present invention relates to a method and composition of an oral preparation of itraconazole, an excellent azole antifungal drug. More particularly, it relates to an oral preparation of itraconazole having improved bioavailability, which is prepared by following steps of: i) dissolving itraconazole and bydrophilic polymer with solvent, ii) spray-drying said mixture, and iii) preparing the solid dispersions for oral preparation. The solid dispersions prepared in this invention may be useful in preparing tablets, granules and other oral dosage forms.
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Number of Claims:
4
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Published
November 26, 2002
Application Number
09/582,536
Filed
June 29, 2000
US Classification
424/464   424/451 424/455 424/456 424/458 424/469 424/489
Int'l Classification
A61K   9/16   (20060101)   A61K   9/14   (20060101)   A61K   31/496   (20060101)  
Examiner
Assistant Examiner
Attorney/Law Firm
Priority Data
Dec 31, 1997 [KR] 97-81947 Jul 10, 1998 [KR] 98-27730
USPTO Field of Search
424/464   424/469   424/451   424/455   424/456   424/458   424/489  
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