A controlled atmosphere incubator having an interior chamber surrounded by a heated water jacket. A glass access door of the chamber is directly heated by a clear, electrically conductive coating. The door is sealed against the perimeter of the opening by a readily replaceable gasket and is field reversible due to unique hinge mounting assemblies. An easily accessed blower assembly is located within the chamber and includes a HEPA filter readily replaceable by the user from within the chamber. A filtered air exchange system is provided for limiting the maximum level of humidity in the chamber. The incubator control maintains constant power output from the blower motor so that the heat output of the motor is also constant. A voltage compensated temperature control is also provided for the heaters associated with the water jacket. Compensation for environmental conditions inside the chamber is also provided by the control for producing more accurate readings of carbon dioxide levels. When an infrared carbon dioxide sensor is used, the control provides a unique calibration method which does not necessitate the use of conventional tanks of calibration gas mixtures.
This is application is a divisional of U.S. application Ser. No. 09/615,270 filed Jul. 13, 2000, now abandoned which is a divisional application of U.S. application Ser. No. 09/286,545 filed Apr. 5, 1999, now U.S. Pat. No. 6,117,687, which is a divisional of U.S. application Ser. No. 09/110,574 filed Jul. 6, 1998, now abandoned, which is a divisional application of application Ser. No. 08/599,150 filed Feb. 9, 1996, now U.S. Pat. No. 5,792,427.
An environmental simulation test utilizes various temperatures and exposure times while exposing a test item to wet and dry conditions. In one example a marine environment where there is some pollution is simulated using a 24 hour test cycle that may be repeated as many days as necessary. The test cycle includes spraying a solution onto a test item and then cyclically exposing the test item to dry and humidified conditions.
A carbon dioxide gas measurement and control system and method which comprises a thermal conductivity absolute humidity sensor which measures carbon dioxide during dynamic temperature and humidity changes by isolating the particular sensor response for absolute humidity and temperature, i.e., Vm(D,T) in order to track carbon dioxide concentration.
An incubation and storage device, in particular for specimens of organic material, is provided. Specifically, boundary surfaces of the inner space of the incubation and storage device are thermally connected to heat transfer elements that are attached on the outside of the device. The heat transfer elements have a liquid heat carrier circulating through them, where the heating and/or cooling of the inner space takes indirectly via the liquid heat carrier. Here a heater for heating and an evaporator for cooling the heat carrier are provided. The heat transfer elements can for example, be box shaped or designed as tubular coils. Through the use of a liquid heat carrier, the necessary temperature constancy inside the device is achieved.
An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, preforming in analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.
An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a specimen sample, incubating the sample at prescribed temperatures for prescribed periods, preforming an analyte isolation procedure, and ascertaining the presence of a target analyte. An automated receptacle transporting system moves the reaction receptacles from one station to the next. The analyzer further includes devices for carrying a plurality of specimen tubes and disposable pipette tips in a machine-accessible manner, a device for agitating containers of target capture reagents comprising suspensions of solid support material and for presenting the containers for machine access thereto, and a device for holding containers of reagents in a temperature controlled environment and presenting the containers for machine access thereto. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte. The process is performed by automatically moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the separated analyte after the analyte separation step and before a final incubation step.