February 4, 2003

Aromatic dehydroamino acids are disclosed that are active as LFA-1 arnagonists This activity enables these compounds to prevent inflammation which is a consequence of T cell activation and accordingly reduce or eliminate inflammatory skin disease psoriasis.

118

February 4, 2003

09/754,888

January 5, 2001

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C07C   311/46   (20060101)   C07C   233/85   (20060101)   C07C   233/00   (20060101)   C07C   311/00   (20060101)   C07C   233/87   (20060101)   C07D   209/00   (20060101)   C07D   403/12   (20060101)   C07D   233/00   (20060101)   C07D   211/34   (20060101)   C07D   235/00   (20060101)   C07D   233/26   (20060101)   C07D   213/00   (20060101)   C07D   285/14   (20060101)   C07D   401/00   (20060101)   C07D   403/00   (20060101)   C07F   9/40   (20060101)   C07F   9/572   (20060101)   C07D   401/12   (20060101)   C07F   9/6524   (20060101)   C07F   9/6558   (20060101)   C07D   211/00   (20060101)   C07D   249/08   (20060101)   C07D   237/00   (20060101)   C07D   237/28   (20060101)   C07D   239/52   (20060101)   C07D   209/08   (20060101)   C07D   235/16   (20060101)   C07D   307/16   (20060101)   C07D   215/14   (20060101)   C07D   249/00   (20060101)   C07D   215/00   (20060101)   C07D   261/08   (20060101)   C07D   317/60   (20060101)   C07D   213/55   (20060101)   C07D   307/00   (20060101)   C07D   239/00   (20060101)   C07D   249/18   (20060101)   C07D   317/00   (20060101)   C07D   409/04   (20060101)   C07D   409/00   (20060101)   C07D   261/00   (20060101)   C07D   277/62   (20060101)   C07D   271/00   (20060101)   C07D   333/24   (20060101)   C07D   277/30   (20060101)   C07D   271/12   (20060101)   C07D   277/64   (20060101)   C07D   417/00   (20060101)   C07F   9/00   (20060101)   C07D   277/38   (20060101)   C07D   417/04   (20060101)   C07D   333/60   (20060101)   C07D   333/00   (20060101)   C07D   285/00   (20060101)   C07D   277/00   (20060101)  

This application claims the benefit of U.S. Provisional Application No. 60/181,182, filed on Feb. 9, 2000.

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	7217728 - Diaminopropionic acid derivatives - Owned by Hoffmann-La Roche Inc. (Nutley, NJ) A compound of formula 1a ##STR00001## which is useful for treating reperfusion injury, and salts, prodrugs, and related compounds.
	7491741 - Diaminopropionic acid derivatives - Owned by Hoffmann-La Roche Inc. (Nutley, NJ) A compound of formula 1a ##STR00001## which is useful for treating reperfusion injury, and salts, prodrugs, and related compounds.