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Automated detection apparatus with a conveying means for test columns
   
Document Number
US Patent 6531285
Issued Date
March 11, 2003
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Inventors
Chen; Hai Shene (Toronto, Ontario,CA)
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Abstract
An apparatus and method for detecting the presence of at least two predetermined known materials in a test sample are disclosed. The apparatus includes a sample addition station for adding a sample to a test column in the apparatus, a reagent station, a washing station, a detection station for detecting signals on the snares of the test column due to the presence of the predetermined known materials in the sample, and conveying means for conveying the test column from the sample addition station to the reagent station, washing station, and detection station. The test sample is introduced into a test column which has at least two snares for capturing the predetermined known materials, and the snares are separate spatially one from another. Each snare has a capture material specific to the associated predetermined known material. The detection station has a plurality of detectors for detecting signals on the snares of the test column due to the presence of the predetermined known materials in the sample. The method is useful for detection of pathogens, DNA and RNA.
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Number of Claims:
12
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Owner
Published
March 11, 2003
Application Number
09/671,398
Filed
September 27, 2000
US Classification
435/6   210/198.2 210/635 210/636 210/656 210/657 250/252.1 250/261 250/370.1 422/50 422/52 435/283.1 435/285.1 435/286.5 435/287.2 435/91.1 435/91.2 436/518 436/536 536/22.1 536/23.1 536/24.3 536/24.31 536/24.32 536/24.33
Int'l Classification
C12Q   1/68   (20060101)   C12N   5/06   (20060101)   G01N   33/543   (20060101)   G01N   33/569   (20060101)   A61K   48/00   (20060101)   A61K   35/12   (20060101)  
Examiner
Parent Case
CROSS REFERENCE TO RELATED APPLICATION This application is a division of patent application Ser. No. 09/093,532, filed Jun. 8, 1998, now U.S. Pat. No. 6,174,733 issued Jan. 16, 2001, which is herein incorporated by reference in its entirety.
Priority Data
Jun 09, 1997 [GB] 9711941
USPTO Field of Search
435/6   435/91.1   435/91.2   435/283.1   435/285.1   435/286.5   435/286.6   435/287.2   436/518   436/536   422/50   422/52   536/22.1   536/23.1   536/24.3   536/24.31   536/24.32   536/24.33   210/656   210/635   210/636   210/657   210/198.2   250/252   250/261   250/370.11  
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