Methods and chewing gum formulations for delivering a medicament, namely sildenafil citrate, to an individual are provided. Further, an improved dosage form and method of treating erectile dysfunction are provided. Methods of treating esophageal spasms, dysphagia, and gastroparesis utilizing chewing gum formulations containing sildenafil citrate are also provided.
This application is a divisional of U.S. patent application Ser. No. 09/714,571, filed on Nov. 16, 2000, now U.S. Pat. No. 6,531,114, which is a continuation-in-part patent application of U.S. patent application, Ser. No. 09/286,818, filed on Apr. 6, 1999 and U.S. patent application Ser. No. 09/621,780 filed on Jul. 21, 2000 which is a continuation of PCT/US99/29792, filed Dec. 14, 1999, patent application WO 00/35298.
A method of making coated chewing gum products comprises the steps of providing chewing gum cores; providing a first coating syrup comprising a bulk sweetener; providing an aldehyde flavor; providing a second coating syrup separate from the first coating syrup and comprising a dipeptide sweetener; and applying the first and second coating syrups to the cores and drying the syrups to produce a coating on the cores. Calcium carbonate or another antacid may be incorporated in the coating by being mixed into the first coating syrup or applied as a dry charge.
