September 23, 2003

This invention provides a process to prepare (2R)-anti-5-{3-[4-(10,11-difluoromethanodibenzosuber-5-yl)piperazin-1-yl]- 2-hydroxypropoxy}quinoline.

1

September 23, 2003

10/378,436

March 3, 2003

544/381   544/363

C07D   295/00   (20060101)   C07D   215/00   (20060101)   C07D   215/20   (20060101)   C07D   295/073   (20060101)  

This application is a divisional of U.S. application Ser. No. 09/979,598, filed Nov. 14, 2001, now U.S. Pat. No. 6,570,016 which is a 371 of PCT/US00/11863, filed May 30, 2000 which claims the benefit of U.S. Provisional Application No. 60/137,284 filed Jun. 3,1999, said application of which is entirely incorporated herein by reference.

544/381