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Indenoindolone compounds
   
Document Number
US Patent 6627650
Issued Date
September 30, 2003
Link
Inventors
Wierzbicki; Michel (L'Etang la Ville,FR)
Atassi; Ghanem (Saint Cloud,FR)
Pierre; Alain (Les Alluets le Roi,FR)
Guilbaut; Nicolas (La Celle Saint Cloud,FR)
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Abstract
A compound of formula (I): ##STR1## wherein: R represents hydrogen, optionally substituted alkyl or alkenyl, R.sub.1 to R.sub.8, which may be identical or different, each represents hydrogen, optionally substituted alkyl, hydroxy, acyloxy, optionally substituted amino, carboxy, optionally substituted alkoxy, or alkenyloxy, or one of R.sub.1 to R.sub.8 forms, with another of R.sub.1 to R.sub.8 that is adjacent, an alkylenedioxy group, X represents oxygen or NR.sub.16 wherein R.sub.16 represents hydrogen, alkyl, aryl or arylalkyl, R.sub.9 represents hydrogen, aryl, heteroaryl, or optionally substituted, saturated or unsaturated alkyl, an isomer thereof, or an addition salt thereof with a pharmaceutically acceptable acid or base. Medicinal products containing the same which are useful as anti-cancer agents.
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Number of Claims:
12
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Owner
Les Laboratoires Servier (Neuilly-sur-Seine,FR)
Published
September 30, 2003
Application Number
10/171,191
Filed
June 13, 2002
US Classification
514/410   548/420
Int'l Classification
C07D   209/00   (20060101)   C07D   401/12   (20060101)   C07D   401/00   (20060101)   C07D   491/04   (20060101)   C07D   491/00   (20060101)   C07D   405/00   (20060101)   C07D   405/12   (20060101)   C07D   209/94   (20060101)   C07D   409/00   (20060101)   C07D   409/12   (20060101)  
Examiner
Assistant Examiner
Attorney/Law Firm
Priority Data
Jun 13, 2001 [FR] 01 07718
USPTO Field of Search
548/127   548/491   548/420   546/201   546/232   546/251   568/584   514/323   514/339   514/361   514/410  
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