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Swainsonine compounds as inhibitors of toxin receptor expression
   
Document Number
US Patent 6670374
Issued Date
December 30, 2003
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Inventors
Anderson; Robin C. (College Station, TX)
Droleskey; Robert E. (College Station, TX)
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Abstract
The invention provides a method for treating infections in animals which are caused by toxin-producing enteric bacterial pathogens, including Shigella species, enterohemorrhagic E. coli, and enterotoxigenic E. coli. Receptors expressed by animal cells which typically recognize these bacterial toxins may be modified by administration of swainsonine compounds to the animal, thereby effectively inhibiting toxin binding to the cells.
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Number of Claims:
19
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Published
December 30, 2003
Application Number
10/166,974
Filed
June 11, 2002
US Classification
514/299  
Int'l Classification
A61K   31/44   (20060101)  
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USPTO Field of Search
514/299  
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