The present invention provides methods of treating or preventing fungal infections in a host comprising administering a treatment effective or treatment effective amount of a yeast NAD synthetase inhibitor compound. The invention further provides a method of killing yeast comprising administering a yeast NAD synthetase compound that selectively binds to catalytic sites in yeast whereby the yeast is killed.
CROSS REFERENCE TO RELATED APPLICATIONS
This application is related to copending provisional application Ser. No. 60/141,43, filed Jun. 29, 1999, which is incorporated by reference, and claims the benefit of its earlier filing date under 35 USC Section 119(e).
Compounds of formula I are described: ##STR00001## along with compositions thereof, methods of use thereof (particularly as fungicides), and methods of making the same.
