A glucose measuring device for determining the concentration of glucose in intravascular blood within a body part of a subject. The device includes at least one light source having a wavelength of 650, 880, 940 or 1300 nm to illuminate the fluid. At least one receptor (14) associated with the light source (12) for receiving light and generating a transmission signal representing the light transmitted is also provided. A support piece is including for supporting the light source associated with the respective receptor. The support piece is adapted to engage a body part of a subject. Finally, a signal analyzer determines the glucose concentration in the blood of the subject. A method for determining the glucose concentration is also provided which calibrates a measuring device and sets the operating current for illuminating the light sources during operation of the device. Once a transmission signal is generated by receptors (14) receiving light via the light source and illuminated blood, and the high and low values from each of the signals are selected and stored in the device (20), the values are subtracted to obtain a single transmission value for each of the light sources. These calculated values are then compared to a database of target transmission values, either using a neural network, or directly compared to determine the glucose concentration, which value is then displayed (28) on the device.
Applicant hereby claims priority to PCT application PCT/US97/08852, filed Jun. 5, 1997, and this application is a continuation-in part of Ser. No. 08/803,066 U.S. Pat. No. 5,910,109 filed Feb. 20,1997.
