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Document Number
US Patent 6797274
Issued Date
September 28, 2004
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Abstract
The invention provides BASB047, BASB054, BASB068 and BASB069 polypeptides, and polynucleotides encoding BASBO47, BASB054, BASB068 and BASB069 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses.
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Number of Claims:
10
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Published
September 28, 2004
Application Number
09/889,746
Filed
December 31, 2001
US Classification
424/250.1   424/184.1 424/185.1 424/190.1 424/249.1 435/243 435/252.3 435/69.1 435/69.3 530/300 530/350 536/23.1 536/23.7 536/24.1 536/24.32
Int'l Classification
C07K   14/195   (20060101)   C07K   14/22   (20060101)  
Assistant Examiner
Priority Data
Jan 22, 1999 [GB] 9901368 Jan 28, 1999 [GB] 9901944 Jan 29, 1999 [GB] 9902086 Feb 15, 1999 [GB] 9903417 Feb 16, 1999 [GB] 9903535
USPTO Field of Search
424/154.1   424/155.1   424/190.1   424/249.1   424/250.1   530/300   530/350   536/23.1   536/23.7   536/26.1   536/26.32   435/69.1   435/69.3   435/243   435/252.3  
Related Patents
7241867 - Polypeptide encoded by a nucleotide sequence of a nontypeable strain of Haemophilus influenzae genome - Owned by Children's Hospital, Inc. (Columbus, OH) The Board of Regents of The Universoty of Oklahoma (Norman, OK)

The invention relates to the polynucleotide sequence of a nontypeable stain of Haemophilus influenzae (NTHi) and polypeptides encoded by the polynucleotides and uses thereof. The invention also relates to NTHi genes which are upregulated during or in response to NTHi infection of the middle ear and/or the nasopharynx.

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Description
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