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5-(alkylidene-cycloalkyl)-and 5-(alkylidene-heterocyclyl)-pyrazoles
   
Document Number
US Patent 6838458
Issued Date
January 4, 2005
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Abstract
The present invention relates to 5-(alkylidene-cycloalkyl)-pyrazoles and 5-(alkylidene-heterocyclyl)-pyrazoles of the formula I: ##STR1## wherein the ring of the formula (R.sup.5)-A-(SO.sub.m R.sup.4), m, B, ring G, R.sup.1 through R.sup.7 are as defined in the specification, to pharmaceutical compositions containing them and to their medicinal use. The compounds of the invention are useful in the treatment or alleviation of inflammation and other inflammation associated disorders, such as arthritis, colon cancer, and Alzheimer's disease in mammals, preferably humans, dogs, cats and livestock animals.
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Number of Claims:
21
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Owner
Pfizer, Inc. (Groton, CT)
Published
January 4, 2005
Application Number
10/285,746
Filed
November 1, 2002
US Classification
514/242   514/252.05 514/255.05 514/269 514/272 514/341 514/407 544/182 544/238 544/297 544/316 544/405 546/275.4 546/276.1 548/368.1 548/368.4 548/369.1 548/370.1 548/371.1 548/371.7 548/372.1 548/372.5
Int'l Classification
C07D   401/00   (20060101)   C07D   401/04   (20060101)  
Examiner
Parent Case
CROSS-REFERENCE TO RELATED APPLICATION This application claims benefit from U.S. provisional application No. 60/335,736, filed Nov. 2, 2001.
USPTO Field of Search
544/182   544/238   544/297   544/316   544/405   546/275.4   546/276.1   548/368.1   548/368.4   548/369.1   548/369.7   548/370.1   548/370.4   548/370.7   548/371.1   548/371.7   548/372.1   548/372.5   514/242   514/252.05   514/255.05   514/269   514/272   514/341   514/407  
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Claims
Description
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