Novel compounds of formula I, with the exception of i) the racemate of (3-amino-2-hydroxypropyl)phosphinic acid; and ii) (2R/S,3R)-(3-amino-2-hydroxybutyl)phosphinic acid, having affinity to one or more GABA.sub.B receptors, their pharmaceutically acceptable salts, solvates and stereoisomers, as well as processes for their preparation, pharmaceutical compositions containing said therapeutically active compounds and the use of said active compounds in therapy. ##STR1##
This application is a continuation of U.S. patent application Ser. No. 09/786,219, filed Mar. 1, 2001 now U.S. Pat. No. 6,576,626, which is a .sctn.371 of international patent application PCT/SE00/02426, filed Dec. 4, 2000.
Priority Data
Dec 09, 1999 [SE] 9904508 Oct 09, 2000 [SE] 0003640
