Human HADH genes are identified as modulators of the p21 pathway, and thus are therapeutic targets for disorders associated with defective p21 function. Methods for identifying modulators of p21, comprising screening for agents that modulate the activity of HADH are provided.
REFERENCE TO RELATED APPLICATIONS
This application claims priority to U.S. provisional patent application No. 60/305,017 filed Jul. 12, 2001, Ser. No. 60/328,491 filed Oct. 10, 2001, and Ser. No. 60/357,452 filed Feb. 15, 2002. The contents of the prior applications are hereby incorporated in their entirety.