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Modafinil polymorphic forms
   
Document Number
US Patent 6992219
Issued Date
January 31, 2006
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Abstract
Modafinil polymorphic forms of modafinil racemate, methods of preparation thereof, pharmaceutical compositions and methods of therapeutic treatment involving modafinil polymorphic forms.
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Number of Claims:
29
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Owner
Cephalon France (Maisons-Alfort,FR)
Published
January 31, 2006
Application Number
10/635,445
Filed
August 7, 2003
US Classification
564/162  
Int'l Classification
C07C   233/05   (20060101)   A61K   31/165   (20060101)  
Attorney/Law Firm
Parent Case
This application claims benefit of 60/402,064, filed Aug. 9, 2002.
USPTO Field of Search
514/618   564/162  
Related Patents
7132570 - Method for the production of crystalline forms and crystalline forms of optical enantiomers of modafinil - Owned by Cephalon France (Maisons-Alfort Cedex,FR)

The invention relates to a process for the preparation of crystalline forms of the optical enantiomers of modafinil, comprising stages comprising: i) dissolving one of the optical enantiomers of modafinil in a solvent other than ethanol, ii) crystallising the modafinil enantiomer, iii) recovering the crystalline form of the modafinil enantiomer so obtained. The invention also relates to a process for the preparation of the optical enantiomers of modafinil.

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