or
Bookmark and Share
Liver X receptor agonists
   
Document Number
US Patent 7012069
Issued Date
March 14, 2006
Link
Inventors
Map
Abstract
A compound of formula (I): ##STR00001## Each of R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.4', R.sub.5, R.sub.6, R.sub.7, R.sub.11, R.sub.12, R.sub.15, R.sub.16, and R.sub.17, independently, is hydrogen, halo, alkyl, haloalkyl, hydroxy, amino, carboxyl, oxo, sulfonic acid, or alkyl that is optionally inserted with --NH--, --N(alkyl)--, --O--, --S--, --SO--, --SO.sub.2--, --O--SO.sub.2--, --SO.sub.2--O--, --SO.sub.3--O--, --CO--, --CO--O--, --O--CO--, --CO--NR'--, or --NR'--CO--; or R.sub.3 and R.sub.4 together, R.sub.4 and R.sub.5 together, R.sub.5 and R.sub.6 together, or R.sub.6 and R.sub.7 together are eliminated so that a C.dbd.C bond is formed between the carbons to which they are attached; each of R.sub.8, R.sub.9, R.sub.10, R.sub.13, and R.sub.14, independently, is hydrogen, halo, alkyl, haloalkyl, hydroxyalkyl, alkoxy, hydroxy, or amino; n is 0, 1, or 2; A is alkylene, alkenylene, or alkynylene; and each of X, Y, and Z, independently, is alkyl, haloalkyl, --OR', --SR', --NR'R'', --N(OR')R'', or --N(SR')R''; or X and Y together are .dbd.O, .dbd.S, or .dbd.NR'; wherein each of R' and R'', independently, is hydrogen, alkyl, or haloalkyl.
Tags:
Description:
Amusing 0%
Clever 0%
Complex 0%
Efficient 0%
Historic 0%
Important 0%
Innovative 0%
Interesting 0%
Practical 0%
Simple 0%
Number of Claims:
8
Comments:
no comments yet
Owner
Published
March 14, 2006
Application Number
10/137,695
Filed
May 2, 2002
US Classification
514/182   552/542
Int'l Classification
A61K   31/56   (20060101)   C07J   9/00   (20060101)  
Parent Case
CROSS REFERENCE TO RELATED APPLICATION Pursuant to 35 U.S.C. .sctn.119(e), this application claims the benefit of prior U.S. provisional application 60/288,643, filed May 3, 2001.
USPTO Field of Search
552/542   514/182  
Related Patents
Claims
Description
About| FAQs| Terms & Disclaimer| Link to Us| Contact Us