The present invention provides a highly sensitive screening assay for the identification of peptide binding partners to virtually any peptide or polypeptide ligand. Utilizing an expression-repression readout system, the inventors have screened libraries of peptides and identified relatively small peptide molecules that bind to the provided target.
The present application claims priority to U.S. Provisional Patent Application Ser. No. 60/182,060, filed Feb. 11, 2000, the entire text of which is specifically incorporated by reference herein without disclaimer.