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Therapeutic composition and a method of coating implantable medical devices
   
Document Number
US Patent 7022334
Issued Date
April 4, 2006
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Inventors
Ding; Ni (San Jose, CA)
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Abstract
A therapeutic composition is provided including a polysaccharide or a cationic peptide dissolved in an organic substance. The polysaccharide can be heparin or a derivative of heparin. The cationic peptide can be L-arginine, oligo-L-arginine or poly-L-arginine. The organic substance can be formamide. A method of coating an implantable medical device is also provided, comprising applying the therapeutic composition to the device and allowing the organic substance to evaporate. The device can be a stent.
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Number of Claims:
61
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Published
April 4, 2006
Application Number
10/104,179
Filed
March 20, 2002
US Classification
424/423   424/424 424/425
Int'l Classification
A61F   2/02   (20060101)  
Attorney/Law Firm
USPTO Field of Search
424/423   424/424   424/425  
Related Patents
7361726 - Poly(hydroxyalkanoate-co-ester amides) and agents for use with medical articles - Owned by Advanced Cardiovascular Systems Inc. (Santa Clara, CA)

Polymers containing poly(hydroxyalkanoate-co-ester amides) and agents for use with medical articles are disclosed along with methods of fabricating medical articles comprising these polymers. The medical articles generally comprise an implantable substrate having a coating containing a poly(hydroxyalkanoate-co-ester amide).

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