An isolated polynucleotide at least 60% homologous to SEQ ID NO: 1, 3, 5 or 18 encoding a SARP polypeptide; vectors comprising a polynucleotide sequence encoding at least 11 consecutive amino acids of .alpha.SARP polypeptide; a host cell transformed with an isolated polynucleotide or vector; antibodies specific for SARP and use of such polynucleotides and antibodies in diagnostic and therapeutic method. Therapeutic uses of antibodies and polynucleotides of sarp. Methods for treating diseases related to the regulation of SARP expression in tissue and bodily fluid samples, including cancers.
CROSS-REFERENCE TO RELATED APPLICATIONS
The present application is a continuation of U.S. patent application Ser. No. 10/146,474, filed May 14, 2002, which is a continuation of U.S. patent application Ser. No. 08/937,067, filed Sep. 24, 1997, now U.S. Pat. No. 6,433,155, which claims priority under 35 U.S.C. .sctn. 119(e) to U.S. Provisional Application Ser. No. 60/026,603, filed Sep. 24, 1996 and U.S. Provisional Application Ser. No. 60/028,363, filed Oct. 11, 1996. U.S. patent application Ser. No. 10/146,474, U.S. patent application Ser. No. 08/937,067, U.S. Provisional Application Ser. No. 60/026,603 and U.S. Provisional Application Ser. No. 60/028,363 are incorporated herein by this reference in their entirety.
An isolated polynucleotide at least 60% homologous to SEQ ID NO: 1, 3, 5 or 18 encoding a SARP polypeptide; vectors comprising a polynucleotide sequence encoding at least 11 consecutive amino acids of .alpha.SARP polypeptide; a host cell transformed with an isolated polynucleotide or vector; antibodies specific for SARP and use of such polynucleotides and antibodies in diagnostic and therapeutic method. Therapeutic uses of antibodies and polynucleotides of sarp. Methods for treating diseases related to the regulation of SARP expression in tissue and bodily fluid samples, including cancers.
