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Process for the synthesis of 1,3-dihydro-2H-3-benzazepin-2-one compounds, and to the application thereof in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
   
Document Number
US Patent 7074920
Issued Date
July 11, 2006
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Inventors
Brigot; Daniel (Sainte-Marie-des-Champs,FR)
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Abstract
Process for the synthesis of compounds of formula (I): ##STR00001## wherein R.sub.1 and R.sub.2, which may be the same or different, each represent a linear or branched (C.sub.1 C.sub.8)alkoxy group or form, together with the carbon atom carrying them, a 1,3-dioxane, 1,3-dioxolane or 1,3-dioxepane ring.Application in the synthesis of ivabradine, addition salts thereof with a pharmaceutically acceptable acid, and hydrates thereof.
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Number of Claims:
11
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Owner
Les Laboratories Servier (Courbevoie,FR)
Published
July 11, 2006
Application Number
11/057,491
Filed
February 14, 2005
US Classification
540/523  
Int'l Classification
C07D   487/00   (20060101)  
Examiner
Attorney/Law Firm
Priority Data
Apr 13, 2004 [FR] 04 03829
USPTO Field of Search
540/523  
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