Interleukin-5 receptor (IL-5R) ligands comprising amino sequences of formula TGGGDGYVX.sub.3VE X.sub.4 ARCPTCK, EGYVX.sub.3VE X.sub.4 ARCPTCK, EGYVX.sub.3VE X.sub.4 ARCPTCR, GYVX.sub.3VE X.sub.4 ARCPTCG, EGYVX.sub.3VE X.sub.4 ARCPTCG, GYVX.sub.3VE X.sub.4 ARCPTCR, and EGYVX.sub.3VE X.sub.4 AACPTCR, and methods of using the same, are described and claimed.
Interleukin-5 receptor (IL-5R) ligands comprising amino sequences of formula TGGGDGYVX.sub.3VEX.sub.4ARCPTCK, EGYVX.sub.3VEX.sub.4ARCPTCK, EGYVX.sub.3VEX.sub.4ARCPTCR, GYVX.sub.3VEX.sub.4ARCPTCG, EGYVX.sub.3VEX.sub.4ARCPTCG, GYVX.sub.3VEX.sub.4ARCPTCR, and EGYVX.sub.3VEX.sub.4AACPTCR, and methods of using the same, are described and claimed.
The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (EPO-R). The invention also relates to therapeutic methods using such peptide compounds to treat disorders associated with insufficient or defective red blood cell production. Pharmaceutical compositions, which comprise the peptide compounds of the invention, are also provided.