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Formulation of boronic acid compounds
   
Document Number
US Patent 7109323
Issued Date
September 19, 2006
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Abstract
The invention relates to the formulation of pharmaceutical compounds. More particularly, the invention provides stable, pharmaceutically acceptable compositions prepared from boronic acid compounds and methods for preparing the compositions. The invention also provides novel boronate ester compounds. The invention further provides boronic acid anhydride compounds useful in the methods of the invention.
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Number of Claims:
12
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Published
September 19, 2006
Application Number
10/744,843
Filed
December 23, 2003
US Classification
536/53   530/320 536/17.1 544/229
Int'l Classification
C07H   3/00   (20060101)   A61K   33/22   (20060101)   A61K   38/00   (20060101)   C07F   5/02   (20060101)   C07K   9/00   (20060101)  
Examiner
Assistant Examiner
Parent Case
CROSS-REFERENCE TO RELATED APPLICATIONS This patent application is a continuation of U.S. patent application No. 10/056,563, now U.S. patent 6,699,835, filed Jan. 25, 2002 which claims the benefit of U.S. Provisional Patent Application No. 60/264,160, filed Jan. 25, 2001.
USPTO Field of Search
536/53   536/17.1   514/2   514/18   514/19   514/64   544/229   530/320   558/286  
Related Patents
7531526 - Boronic ester and acid compounds, synthesis and uses - Owned by Millennium Pharmaceuticals, Inc. (Cambridge, MA)

Disclosed herein is a method for reducing the rate of degradation of proteins in an animal, comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses.

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