The invention relates to the formulation of pharmaceutical compounds. More particularly, the invention provides stable, pharmaceutically acceptable compositions prepared from boronic acid compounds and methods for preparing the compositions. The invention also provides novel boronate ester compounds. The invention further provides boronic acid anhydride compounds useful in the methods of the invention.
CROSS-REFERENCE TO RELATED APPLICATIONS
This patent application is a continuation of U.S. patent application No. 10/056,563, now U.S. patent 6,699,835, filed Jan. 25, 2002 which claims the benefit of U.S. Provisional Patent Application No. 60/264,160, filed Jan. 25, 2001.
Disclosed herein is a method for reducing the rate of degradation of proteins in an animal, comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses.