The present invention is related to novel processes for preparing anhydrous and hydrated forms of piperidine derivatives, polymorphs and pseudomorphs thereof of the formulas ##STR00001## which are useful as antihistamines, antiallergic agents and bronchodilators.
This is a continuation of application Ser. No. 09/803,389, filed Mar. 9, 2001 now abandoned, which is a continuation of application Ser. No. 09/213,554, filed Dec. 17, 1998, now abandoned, which is a continuation of application Ser. No. 08/815,640, filed Mar. 13, 1997, now abandoned, which is a continuation of application Ser. No. 08/417,161, filed Apr. 11, 1995, now abandoned, which is a continuation-in-part of Ser. No. 08/245,731, filed May 18, 1994, now abandoned.
The invention relates to polymorphs of zoledronic acid and zoledronate sodium salts, amorphous zoledronate sodium salt, processes for making the polymorphs and amorphous zoledronate sodium salt, and pharmaceutical compositions containing the polymorphs and amorphous zoledronate sodium salt.
The invention relates to polymorphs of zoledronic acid and zoledronate sodium salts, amorphous zoledronate sodium salt, processes for making the polymorphs and amorphous zoledronate sodium salt, and pharmaceutical compositions containing the polymorphs and amorphous zoledronate sodium salt.
The invention relates to polymorphs of zoledronic acid and zoledronate sodium salts, amorphous zoledronate sodium salt, processes for making the polymorphs and amorphous zoledronate sodium salt, and pharmaceutical compositions containing the polymorphs and amorphous zoledronate sodium salt.
