US Patent 7157457 - Compounds useful in the treatment of inflammatory diseases

Compounds useful in the treatment of inflammatory diseases

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Document Number

US Patent 7157457

Issued Date

January 2, 2007

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Inventors

Ancliff; Rachael Anne (Stevenage,GB)

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Cook; Caroline Mary (Stevenage,GB)

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Eldred; Colin David (Stevenage,GB)

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Gore; Paul Martin (Stevenage,GB)

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Harrison; Lee Andrew (Stevenage,GB)

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Hodgson; Simon Teanby (Stevenage,GB)

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Judd; Duncan Bruce (Stevenage,GB)

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Keeling; Suzanne Elaine (Stevenage,GB)

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Lewell; Xiao Qing (Stevenage,GB)

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Robertson; Graeme Michael (Stevenage,GB)

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Swanson; Stephen (Stevenage,GB)

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Abstract

There are provided according to the invention, novel compounds of formula (I) ##STR00001## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, X, a, b and Z are as defined in the specification, processes for preparing them, formulations containing them and their use in therapy for the treatment of inflammatory diseases.