The invention relates to a system for synthesizing radiopharmaceuticals employing one or more single-use integrated kits of materials, valves and vessels fitted to one or more stationary apparatus in the manner that the kit can be safely ejected and disposed of without manual operations. Fluidic connections on the kits are made with flexible tubing that can be inserted into the various components by hand. This, along with the use of flexible configuration rotary valves, makes it possible to configure them to carry out a variety of processes.
A manufacturing method for .sup.123I-ADAM and an automatic manufacturing device thereof are disclosed. The manufacturing process for .sup.123I-ADAM consists of four steps-add [.sup.123I] ammonium iodide solution, make oxidation reaction occur, terminate the reaction and neutralize the solution, filter and collect the filtrate. The automatic manufacturing device includes a plurality of units for taking each of the four steps that is disposed inside a chassis and is operated by automatic control. Users only need to put reactants into storage bottles respectively, turn on the power, and initiate the operation system, Then the preparation process of drugs for clinical diagnosis is finished within twenty minutes.
A rod assembly for a fuel bundle of a nuclear reactor may include an upper end piece, lower end piece and a plurality of rod segments attached between the upper and lower end pieces and to each other so as to form an axial length of the rod assembly. The rod assembly may include an adaptor subassembly provided at given connection points for connecting adjacent rod segments or a given rod segment with one of the upper and lower end pieces. The connection points along the axial length of the rod assembly may be located where the rod assembly contacts a spacer in the fuel bundle. One (or more) of the rod segments may include an irradiation target therein for producing a desired isotope when a fuel bundle containing one (or more) rod assemblies is irradiated in a core of the reactor.