Provided are mammalian secreted and non-secreted diabetes mediating proteins, including protective and deleterious diabetes-mediating proteins, as well as polynucleotides encoding same, drug screening methods for identifying a test compound capable of altering the expression of a diabetes-mediating protein, and methods of preventing or ameliorating diabetes by administering a compound capable of the expression of a diabetes-mediating protein.
This application is a continuation of application Ser. No. 10/479,530, filed Dec. 1, 2003, which is a National Stage of PCT/DK02/00368 which application is incorporated herein by reference.
Priority Data
May 29, 2001 [DK] 2001 00852 Mar 22, 2002 [DK] 2002 00446