The present invention provides imprint compositions useful for capturing, isolating, detecting and/or quantifying macromolecules in a sample, methods of making and using the same. Generally, the imprint compositions comprise a matrix material defining an imprint of a template molecule, and the template molecule typically corresponds to a portion of a macromolecule of interest.
This application is a divisional application of application Ser. No. 09/895,643, filed Jun. 28, 2001 now U.S. Pat. No. 6,680,210, which is a divisional application of application Ser. No. 09/507,300, filed Feb. 18, 2000 (U.S. Pat. No. 6,458,599), the entire contents of which are hereby incorporated by reference.