A wire winding device with transmission line is pulled at one end. The retaining end module and the telescopic end module are fixed together. The transmission line of the transmission line can be received in the spacing layer. In use only one end of the transmission line is pulled out. The transmission line will can be arranged orderly. The wire winding device has the function of adjusting the length of the earphone at any time without affecting the data reading or playing. Thereby the transmission line can be connected to various devices, such as earphones, USB connectors or signal connectors, to be connected to various electronic devices, such as computers, and mobile phones, etc. Thereby structure is simple and can be operated easily.
