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Document Number
US Patent 7314940
Issued Date
January 1, 2008
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Abstract
The present invention provides novel compounds of formula I ##STR00001## and their use in the inhibition of c-Jun N-terminal kinases. The present invention further provides the use of these compounds in medicine, in particular in the prevention and/or treatment of neurodegenerative disorders related to apoptosis and/or inflammation.
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Number of Claims:
12
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Owner
Eisai Co., Ltd. (Tokyo,JP)
Published
January 1, 2008
Application Number
10/473,578
Filed
April 4, 2002
US Classification
548/302.7   546/118 546/121
Int'l Classification
A61K   31/4184   (20060101)   A61K   31/4188   (20060101)   C07D   235/02   (20060101)   C07D   487/04   (20060101)   C07D   519/00   (20060101)  
Priority Data
Apr 06, 2001 [GB] 0108770.9
USPTO Field of Search
548/302.7  
Related Patents
7534800 - 7-azaindoles as inhibitors of c-Jun N-terminal kinases for the treatment of neurodegenerative disorders - Owned by Eisai R & D Development Co., Ltd. (Tokyo,JP)

The present invention relates to novel 3,5-substituted 7-azaindole compounds of formula (I), their use in the inhibition of c-Jun N-terminal kinases, their use in medecine and particularly in the prevention and/or treatment of neurodegenerative disorders related to apoptosis and/or inflammation. The invention also provides processes for manufacture of said compounds, compositions containing them and processes for manufacturing such compositions. ##STR00001##

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Description
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