The present invention relates to an oil in water emulsion vaccine composition. In particular, the present invention relates to a vaccine adjuvant formulation based on oil in water emulsion comprising a metabolisable oil and a saponin, wherein the oil and a saponin are present in a ratio of between 1:1 and 200:1. The invention further relates to methods for preparing the emulsion and its use in medicine.
This is a continuation of application Ser. No. 09/486,997, filed Jul. 31, 2000; now abandoned which is a 371 of International Application No. PCT/EP98/05715, filed 2 Sep. 1998; which claims priority from the following Great Britain Application Nos.: GB 9718902.1, filed 5 Sep. 1997 and GB 9720982.9, filed 2 Oct. 1997.
Priority Data
Sep 05, 1997 [GB] 9718902.1 Oct 02, 1997 [GB] 9720982.9
