Disclosed herein are antigens that stimulate protective antibodies against enterotoxigenic Escherichia coli. Also disclosed herein are proteins encoded by cssA and cssB genes as well as constructs containing the genes and methods of using thereof.
This application is a continuation of patent application U.S. Ser. No. 09/479,877 filed Jan. 10, 2000 now U.S. Pat. No. 7,118,758, which is allowed and is a continuation of patent application U.S. Ser. No. 08/788,145 filed Jan. 24, 1997, which is abandoned and is a continuation-in-part of patent application U.S. Ser. No. 08/243,482 filed May 13, 1994, which is abandoned.