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Device for capturing beads and method and apparatus for arraying beads
   
Document Number
US Patent 7358098
Issued Date
April 15, 2008
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Abstract
Beads having diameters of several tens of micrometers to several millimeters and immobilized with biomolecules are captured by one kind of bead capturing nozzle one by one without fail. Using a bead holding plate having a plurality of wells each of which holds a plurality of the beads and a solution, a vibration generator mounted with a stage to attach the bead holding plate, and a bead capturing nozzle for bead capture connected to a suction pump, only a single bead is captured at the tip of the bead capturing nozzle by inserting the nozzle having an inner diameter smaller than the beads and a negative pressure inside created by the pump into the solution to allow the nozzle to come in contact with the beads in the well, applying a vibration to the bead holding plate by the vibration generator, and withdrawing the bead capturing nozzle into the air.
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Number of Claims:
18
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Published
April 15, 2008
Application Number
11/195,701
Filed
August 3, 2005
US Classification
436/518  
Int'l Classification
G01N   33/543   (20060101)  
Examiner
Priority Data
May 13, 2005 [JP] 2005-141569
USPTO Field of Search
436/518   435/283.1   435/286.7   435/8   435/9   435/10   435/11   435/12   435/13   435/14   435/15   435/16   435/17   435/18   435/19   435/20   435/21   435/22   435/23   435/24   435/25   435/26   435/27.3   435/288.4   422/58   422/62   422/63   422/64   422/65   422/66  
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