or
Bookmark and Share
Compositions and method for inhibiting TGF-.beta.
   
Document Number
US Patent 7361669
Issued Date
April 22, 2008
Link
Inventors
Mehrotra; Mukund (South San Francisco, CA)
Map
Abstract
This invention provides compounds that are inhibitors of the TGF-.beta. signaling pathway. The compounds are represented by formula I: ##STR00001## where A' is N or CH; Ring B is preferably an triazolyl, imidazolyl, or thiazolyl ring; --X-D- is a linker group; and G is an optionally substituted aryl or heteroaryl ring. The compounds are useful for treating cardiovascular disease.
Tags:
Description:
Amusing 0%
Clever 0%
Complex 0%
Efficient 0%
Historic 0%
Important 0%
Innovative 0%
Interesting 0%
Practical 0%
Simple 0%
Number of Claims:
7
Comments:
no comments yet
Owner
Published
April 22, 2008
Application Number
10/747,531
Filed
December 29, 2003
US Classification
514/315  
Int'l Classification
A61K   31/445   (20060101)  
Parent Case
This application claims the benefit under 35 U.S.C. .sctn. 119(e) of U.S. Provisional Application No. 60/437,679, filed Jan. 2, 2003.
USPTO Field of Search
Related Patents
Claims
Description
About| FAQs| Terms & Disclaimer| Link to Us| Contact Us