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Biological process for the conversion of nitroarenes to ortho-aminophenols using recombinant E. coli strains
 
   
Document Number
US Patent 7364881
Issued Date
April 29, 2008
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Abstract
A process for biological production of ortho-aminophenols from nitroaromatic compounds using recombinant E. Coli strains. The process uses an enzyme system that makes use of a nitroreductase enzyme that initially reduces the nitroarene to the hydroxylaminoarene and a mutase enzyme that converts the hydroxylaminoarene to an ortho-aminophenol.
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Number of Claims:
5
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Published
April 29, 2008
Application Number
11/108,147
Filed
April 11, 2005
US Classification
435/128   435/170 435/193 435/253.3 536/23.2
Int'l Classification
C12P   13/00   (20060101)   C07H   21/04   (20060101)   C12N   1/20   (20060101)  
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Parent Case
CROSS REFERENCE TO RELATED APPLICATION This application claims priority of the filing date of Provisional Application Ser. No. 60/592,022, filed Jul. 29, 2004, the entire contents of which are incorporated herein by reference.
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