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Adduct of topiramate and tramadol hydrochloride and uses thereof
Document Number
US Patent 7378519
Issued Date
May 27, 2008
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Inventors
Naeff; Rainer
(Schlatt,CH)
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Spycher-Huber; Sonja
(Benken,CH)
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Hunziker; Thomas
(Schaffhausen,CH)
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Laufer; Guenter
(Singen,DE)
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Abstract
Processes for isolation and purification of enantiomerically enriched compositions comprising tramadol and topiramate, and also for the subsequent isolation of 1S,2S-tramadol hydrochloride, are disclosed herein.
Patent Report
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adduct
topiramate
tramadol
hydrochloride
uses
thereof
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Clever 0%
Complex 0%
Efficient 0%
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Important 0%
Innovative 0%
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Practical 0%
Simple 0%
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Number of Claims:
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Owner
Cilag GmbH International
(Schaffhausen,CH)
Published
May 27, 2008
Application Number
10/514,739
Filed
May 16, 2003
US Classification
536/127
536/122 564/355
Int'l Classification
C07H 1/06 (20060101) C07C 215/00 (20060101)
Examiner
Jiang; S. Anna
Assistant Examiner
Crane; L. E.
Priority Data
May 23, 2002 [EP] 02077019
USPTO Field of Search
514/23 514/456 514/643 514/646 536/54 536/120 536/127
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