This invention relates to compounds, which are generally anti-inflammatory and analgesic compounds, and which are represented by Formula I: ##STR00001## wherein A is a --CH.sub.2--, --O--, --S--, or --S(O)--; and the other substituents are as defined in the specification; or individual isomers, mixtures of isomers, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds and methods for their use as therapeutic agents
CROSS-REFERENCE
This application is a continuation of U.S. application Ser. No. 11/065,841 filed Feb. 25, 2005, now U.S. Pat. No. 7,074,939, which is a divisional of U.S. application Ser. No. 10/255,89 1, filed Sep. 26, 2002, now U.S. Pat. No. 6,872,744, which claims the benefit of priority to U.S. Provisional Application No. 60/325,389, filed Sep. 27, 2001, all incorporated herein by reference in their entirety.