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Method of identifying compounds that induce cell death by necrosis
   
Document Number
US Patent 7439031
Issued Date
October 21, 2008
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Inventors
Thompson; Craig B. (Merion Station, PA)
Zong; Wei-Xing (Philadelphia, PA)
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Abstract
The present invention provides methods of identifying and/or detecting anti-cancer agents. The present invention provides methods of identifying and/or detecting compounds that can activate PARP and/or induce necrosis. The present invention also provides for methods of treating cancer in an individual. The present invention also provides kits for identifying and/or detecting anti-cancer agents.
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Number of Claims:
13
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Published
October 21, 2008
Application Number
11/013,574
Filed
December 15, 2004
US Classification
435/7.23   435/4
Int'l Classification
G01N   33/574   (20060101)   C12Q   1/00   (20060101)  
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Assistant Examiner
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Parent Case
CROSS-REFERENCE TO RELATED APPLICATIONS This application claims priority to U.S. Provisional Application Ser. No. 60/529,642, filed Dec. 15, 2003, which is incorporated herein by reference in its entirety.
USPTO Field of Search
435/7.1  
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