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RAGE protein derivatives
   
Document Number
US Patent 7470521
Issued Date
December 30, 2008
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Abstract
The present invention is drawn to fusion proteins comprising a Receptor for Advanced Glycation Endproducts (RAGE) and an immunoglobulin element. The invention also encompasses methods of treating a condition characterized by activation of an inflammatory cytokine cascade comprising administering such fusion proteins. The invention is also drawn to nucleic acids encoding the fusion proteins, as well as vectors and cells comprising such nucleic acids.
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Number of Claims:
24
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Published
December 30, 2008
Application Number
11/186,422
Filed
July 20, 2005
US Classification
435/69.1   424/192.1 435/252.3 435/325 435/344.1 435/69.7 435/91.4 536/23.4
Int'l Classification
C12P   21/06   (20060101)   A61K   39/00   (20060101)   C07H   21/04   (20060101)   C12N   1/20   (20060101)   C12N   15/64   (20060101)   C12N   5/00   (20060101)   C12N   5/16   (20060101)   C12P   21/04   (20060101)  
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Parent Case
RELATED APPLICATION This application claims the benefit of U.S. Provisional Application No. 60/589,678, filed on Jul. 20, 2004, the entire teachings of which are incorporated herein by reference.
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