In its many embodiments, the present invention provides tricyclic compounds of formula I (wherein J.sup.1-J.sup.4, X, and R.sup.1--R.sup.5 are as defined herein) useful as metabotropic glutamate receptor (mGluR) antagonists, particularly as selective metabotropic glutamate receptor 1 antagonists, pharmaceutical compositions containing the compounds, and methods of treatment using the compounds and compositions to treat diseases associated with metabotropic glutamate receptor (e.g., mGluR1) such as, for example, pain, migraine, anxiety, urinary incontinence and neurodegenerative diseases such Alzheimer's disease. ##STR00001##
CROSS-REFERENCE TO RELATED APPLICATIONS
This application claims the benefit of priority of U.S. Provisional application Ser. No. 60/579,920, filed Jun. 15, 2004.
