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Knockout mouse for the tumor suppressor gene ANX7
   
Document Number
US Patent 7504223
Issued Date
March 17, 2009
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Abstract
This invention provides methods, including a method of assessing the prognosis of a breast cancer patient, comprising assaying for loss of heterozygosity at the 10q21 region of the genome of the patient, a method of identifying a probability that a patient with breast cancer has metastasized breast cancer, a method of determining a survival probability of a patient with breast cancer, and a method of identifying a probability that a patient with prostate cancer has a severe form of prostate cancer. This invention also provides assay complexes, including assay complexes which comprise at least one prostate tissue sample or tissue sample extract, an antibody that specifically binds ANX7, and a label, or which comprise at least one breast tissue sample or tissue sample extract, an antibody that specifically binds ANX7, and a label.
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Number of Claims:
17
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Published
March 17, 2009
Application Number
11/017,756
Filed
December 22, 2004
US Classification
435/7.1  
Int'l Classification
G01N   33/53   (20060101)  
Examiner
Parent Case
This application is a continuation-in-part of application Ser. No. 10/834,375, filed Apr. 29, 2004, which is a division of application Ser. No. 09/633,278, filed Aug. 4, 2000 (now U.S. Pat. No. 6,747,187), which claims the right to priority based on Provisional Patent Application No. 60/147,255, filed Aug. 5, 1999. Each of these applications is hereby incorporated herein by reference.
USPTO Field of Search
435/7.1  
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