A tilting inversion exerciser includes a table rotatably supported on a supporting stand for supporting a user, two pivot coupling devices each having a middle axle for pivotally attaching to the supporting stand and each having one arm secured to the side portions of the table for offsetting the table from the axles of the pivot coupling devices, and a rotating device for rotating the pivot coupling device relative to the supporting stand, to rotate the table relative to the supporting stand. The table and the user may be supported and located on or closer to the center of gravity of the supporting stand, for being stably supported on the supporting stand particularly when the user is conducting the inversion exercises.