The present invention provides vaccine compositions comprising an oil-in-water emulsion optionally with 3 De-O-acylated monophosphoryl lipid A and QS21. The vaccine compositions are potent induces of a range of immune responses.
CROSS REFERENCE TO RELATED APPLICATIONS
This application is a continuation of U.S. application Ser. No. 11,200,601 filed Aug. 10, 2005, now U.S. Pat. No. 7,169,391, which is a continuation of application Ser. No. 10/654,279, filed on Sep. 3, 2003, now U.S. Pat. No. 7,029,678, which is a divisional of application Ser. No. 09/513,255, filed Feb. 24, 2000, now U.S. Pat. No. 6,623,739, which is a divisional of application Ser. No. 08/663,289, filed Jul. 2, 1996, now U.S. Pat. No. 6,146,632, which is a 371 of PCT/EP94/04246, filed Dec. 20, 1994, which claims priority to GB 9326253.3, filed Dec. 23, 1993.