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Vanilloid receptor ligands and their use in treatments
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Document Number
US Patent 7511044
Issued Date
March 31, 2009
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Inventors
Wang; Hui-Ling
(Thousand Oaks, CA)
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Balan; Chenera
(Thousand Oaks, CA)
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Doherty; Elizabeth M.
(Newbury Park, CA)
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Falsey; James R.
(Moorpark, CA)
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Gore; Vijay Keshav
(Thousand Oaks, CA)
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Katon; Jodie
(Ventura, CA)
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Norman; Mark H.
(Thousand Oaks, CA)
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Abstract
Pyrimidine ethers and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
Patent Report
Tags:
vanilloid
receptor
ligands
use
treatments
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Number of Claims:
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Owner
Amgen Inc.
(Thousand Oaks, CA)
Published
March 31, 2009
Application Number
11/056,568
Filed
February 11, 2005
US Classification
514/252.14
514/252.18 514/252.19 514/252.2 544/295
Int'l Classification
C07D 403/04 (20060101) A61K 31/496 (20060101)
Examiner
Rao; Deepak
Attorney/Law Firm
Parson; Richard V.
Parent Case
This application claims the benefit of U.S. Provisional Application No. 60/543,896, filed Feb. 11, 2004, which is hereby incorporated by reference.
USPTO Field of Search
544/295 514/252.14 514/252.18 514/252.19 514/252.2
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