A composition comprising a substantially purified compound of the formula: ##STR00001## in combination with at least one additional therapeutic agent, and methods of preventing or treating cancer and a condition treatable by the inhibition of vacuolar-type (H+)-ATPase.
CROSS-REFERENCE TO RELATED PATENT APPLICATIONS
This patent application is a divisional of copending U.S. patent application Ser. No. 10/521,930, filed on Apr. 18, 2005, which is a U.S. national phase of International Patent Application No. PCT/US2003/023290, filed on Jul. 24, 2003, and which claims the benefit of U.S. Provisional Patent Application No. 60/398,092, which was filed on Jul. 24, 2002.