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Interleukin-18 mutants
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Document Number
US Patent 7524488
Issued Date
April 28, 2009
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Inventors
Dinarello; Charles
(Boulder, CO)
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Kim; Soo Hyun
(Denver, CO)
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Abstract
The invention provides mutants of IL-18 with lower affinity to IL-18BP than the wild type IL-18 molecule.
Patent Report
Tags:
interleukin
mutants
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Description:
Amusing 0%
Clever 0%
Complex 0%
Efficient 0%
Historic 0%
Important 0%
Innovative 0%
Interesting 0%
Practical 0%
Simple 0%
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Number of Claims:
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Owner
Ares Trading S.A.
(Aubonne,CH)
Published
April 28, 2009
Application Number
10/094,153
Filed
March 8, 2002
US Classification
424/85.2
530/351
Int'l Classification
A61K 45/00 (20060101) A61K 38/20 (20060101)
Examiner
Landsman; Robert
Assistant Examiner
Hissong; Bruce D
Attorney/Law Firm
Nixon Peabody LLP
Parent Case
This application claims the benefit of U.S. Provisional Application No. 60/274,327, filed Mar. 8, 2001.
USPTO Field of Search
530/350 536/23.1 514/2
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