Pyrazolopyridin-4-amines, pyrazoloquinolin-4-amines, pyrazolonaphthyridin-4-amines, and 6,7,8,9-tetrahydropyrazoloquinolin-4-amines, pharmaceutical compositions containing the compounds, intermediates, methods of making, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases, are disclosed.
CROSS REFERENCE TO RELATED APPLICATIONS
This application is a continuation-in-part of International Patent Application No. PCT/US04/32480, with an international filing date of Oct. 1, 2004, which claims the benefit under 35 U.S.C. .sctn. 119(e) of U.S. Provisional Application Ser. Nos. 60/508,352, filed Oct. 3, 2003, 60/554,680, filed Mar. 19, 2004, and 60/603,303, filed Aug. 20, 2004, all of which are incorporated herein by reference.