This invention relates to compositions comprising carbon-based diazeniumdiolates that release nitric oxide (NO). The carbon-based diazeniumdiolated molecules release NO spontaneously under physiological conditions without subsequent nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated molecules, compositions comprising such molecules, methods of using such compositions, and devices employing such molecule compositions.
This application claims priority under 35 U.S.C. .sctn. 120 to U.S. Provisional Application No. 60/542,298 filed Feb. 9, 2004, and to PCT/US05/00175 filed Jan. 6, 2005, each of which is incorporated by reference in its entirety.