The invention provides methods for treating beta-Amyloid protein-induced disease, pharmaceutical compositions and compounds useful for the same, and the use of these compounds for the manufacture of a medicament for treating the same. More particularly, the invention relates to the use of natural product compounds isolated from turmeric, gingko biloba, and ginger, and synthetic chemical analogues thereof, for the treatment of a beta-Amyloid protein-induced disease.
This application is a divisional application of U.S. patent application Ser. No. 10/111,039, filed Apr. 19, 2002, (now U.S. Pat. No. 6,887,898) and is copending with U.S. patent application Ser. No. 11/084,316, filed Mar. 18, 2005, which is a continuation of U.S. patent application Ser. No. 10/111,039, filed Apr. 19, 2002, (now U.S. Pat. No. 6,887,898). U.S. patent application Ser. No. 10/111,039, filed Apr. 19, 2002, is the U.S. National Phase of International Patent Application No. PCT/US00/41436 filed Oct. 23, 2000, which claims the benefit of priority of European Patent Application No. 00986827.4, filed Oct. 23, 2000 and U.S. Provisional Patent Application No. 60/161,145 filed Oct. 22, 1999. The disclosures of all priority applications are incorporated herein by reference in their entireties.
This application claims priority from U.S. Provisional Application Ser. No. 60/161,145 filed Oct. 22, 1999.